منابع مشابه
The SOS Response of Biofilms
Background: Biofilms predominate in nearly all nutrient-sufficient ecosystems, both natural and clinical. In clinical settings, bacteria often encounter antimicrobial and DNA damaging agents. Factual evidence shows that more and more biofilm inducing antimicrobials trigger the SOS response of bacteria. This triggering leads to a link between biofilms and SOS. The purpose of this article is to r...
متن کاملDNA gyrase, topoisomerase IV, and the 4-quinolones.
For many years, DNA gyrase was thought to be responsible both for unlinking replicated daughter chromosomes and for controlling negative superhelical tension in bacterial DNA. However, in 1990 a homolog of gyrase, topoisomerase IV, that had a potent decatenating activity was discovered. It is now clear that topoisomerase IV, rather than gyrase, is responsible for decatenation of interlinked chr...
متن کاملThe SOS response controls integron recombination.
Integrons are found in the genome of hundreds of environmental bacteria but are mainly known for their role in the capture and spread of antibiotic resistance determinants among Gram-negative pathogens. We report a direct link between this system and the ubiquitous SOS response. We found that LexA controlled expression of most integron integrases and consequently regulated cassette recombinatio...
متن کاملThe SOS response regulates adaptive mutation.
Upon starvation some Escherichia coli cells undergo a transient, genome-wide hypermutation (called adaptive mutation) that is recombination-dependent and appears to be a response to a stressful environment. Adaptive mutation may reflect an inducible mechanism that generates genetic variability in times of stress. Previously, however, the regulatory components and signal transduction pathways co...
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ژورنال
عنوان ژورنال: Journal of Medical Microbiology
سال: 1989
ISSN: 0022-2615,1473-5644
DOI: 10.1099/00222615-29-2-139